Season 1

In an unnamed locale resembling Mexico, Nadie, a bounty hunter, is hired to look for Ellis, a young, innocent, amnesiac girl who's currently staying with an elderly fortune teller.

With their vehicle broken down, Ellis and Nadie arrive at a small restaurant owned by a somewhat disgruntled woman named Frida.

Ellis and Nadie take refuge from the rain in an abandoned house near the river, accompanied by the skeletal corpse of the previous owner.

While being pursued by two bounty hunters, Ellis and Nadie take refuge in a convent. The sisters there are eager to offer them protection, with zealous disregard for their own safety.

The girls' jeep gets sabotaged, forcing them to stop in a nearby village for the night. There, Ellis gets kidnapped by a bounty hunter assisted by a local girl who dreams of going to the city, prompting Nadie to mount a rescue.

As the girls stop by another town on their journey south, they run into Miguel, Nadie's old acquaintance. However, she is not overjoyed to see him, as he had deceived her in the past. L.A. steals a kiss from Ellis while she sleeps.

The girls arrive at a fairly luxurious hotel in hope that they can get some decent sleep without interruptions. There they run into Lirio, who is waiting for Ricardo. In the meantime, Ricardo is instructed by Rosenberg to teach L.A. a lesson about controlling his obsession with Ellis.

Nadie receives a gunshot wound when going out buying food. In desperation, Ellis uses her power to remove the bullet from Nadie's body. This event is witnessed by the son of a powerful mafia boss, who proceeds to take her in, hoping to talk her into healing his father's sickness.

An attempt to evade bounty hunters has the heroines trapped inside an abandoned silver mine. There they meet a woman who is digging to find a silver cross, something that everyone in her family wants except for her.

The heroines intervene when a man who runs a local franchise taco restaurant is about to get assaulted. The man offers them to stay for the night and eventually recalls the interesting circumstances as to how he met his wife.

Nadie and Ellis encounter a village where denizens worship a fake witch. With danger of being discovered as a fake, the woman tries to befriend Ellis in order to strengthen her own position.

The heroines encounter Ortega, a man who collect guns and has himself holed up inside an armored van due to his anti-government sentiment.

The heroines end up in a town that is supposedly abandoned due to a disease outbreak.

The episode goes over the events that led to the murder Dr. Heinz Schneider. It shows the burgeoning affection between Schneider and Ellis, as well as Rosenberg engineering things behind Schneider's back.

The heroines meet Ricardo and Lirio in an abandoned hot spring hotel. There they learn that Ricardo is now out of a job, as Rosenberg is forced into early retirement in order to eliminate any link between Project Leviathan and the Central Intelligence Agency.

In response to Nadie's desertion, Blue-Eyes has her bank account frozen. This forces Nadie and Ellis to seek temporary employment in a taco restaurant along the way.

Not having alleviated her financial crisis, Nadie is forced to find work as a bounty hunter again. What she does not know is that Ricardo, in a similar situation due to Rosenberg's downfall, is going after the same target as she is.

Nadie accidentally breaks Ellis's amulet, causing her to get angry, refusing to talk to Nadie anymore. They encounter a roadhouse where an old man offers them a place to stay. It is soon discovered that old man is not what he appears to be.

Ricardo's car breaks down, so Nadie picks him up to the nearest town where he could fix it. A mechanic mistakes Nadie and Ricardo for a couple and offers them free tickets to a fancy restaurant. However, it turns out to be a plot to kidnap Ellis.

L.A. arrives in a town bar, and after being irritated by some of the bar's patrons, kills several of the people there. When Ellis and Nadie arrive in the same town, the police there arrest Nadie and throw her in prison.

Due to Blue-Eyes's inability to capture Ellis, she receives a new order, to eliminate Nadie, with the condition that she must carry out the order herself. In the meantime, Ellis and Nadie are trying to capture a particular vulture after falling for a conman's scam.

Ellis and Nadie's travel and bounty hunting activities eventually lead them into a place of ancient ruins, where Ellis' power is greatly increased by a large Inca Rose atop a stone pillar.

With Nadie currently in the hospital from her injuries, Blue Eyes explains the history of witches and their powers.

Ellis and Nadie finally meet Rosenberg and he announces his intention of killing Nadie in order to awaken the full potential of Ellis's witch powers.

Ellis and Nadie arrive at Wiñay Marka and meet up with Rosenberg.

Some time after Rosenberg's death, Ellis and Nadie find themselves living with and working for a middle-aged husband and wife who run a small café, not knowing of the two girls' previous adventures.